Method for the determination of total components of o-phenylphenol and methrin in insecticides - Master's thesis - Dissertation

O-phenylphenol, methrin, and other compounds in insecticides are analyzed using a multi-component gas chromatography method. This technique utilizes a Flame Ionization Detector (FID) and an HP-1 capillary column to separate and quantify key active ingredients such as o-phenylphenol, repellent ester, dextromethrin, propymethrin, acetylidene, methrin, and cypermethrin. Dibutyl phthalate is used as the internal standard for accurate quantification.

The linear correlation coefficients for these components were found to be highly significant: 0.9988, 0.9994, 0.9999, 0.9999, 0.9999, 1.0000, and 0.9993, respectively. The standard deviations ranged from 0.005 to 0.04, with coefficients of variation between 2.7% and 8.5%. The average recovery rates varied between 99.81% and 100.61%, indicating high accuracy and reliability of the method.

This analytical approach is particularly useful for the rapid screening and qualitative identification of active ingredients in sanitary insecticide products. With over 40 manufacturers in Shanghai and a wide range of product types, there is a growing need for standardized and efficient testing methods. By focusing on commonly used active ingredients, this method allows for flexible adjustments based on the specific composition of each product, ensuring optimal separation and detection performance.

Key words: Gas chromatography; Capillary column; Multi-component analysis; Insecticide; Quality control

The experimental setup includes an Agilent 6890 gas chromatograph equipped with a hydrogen flame ionization detector and a workstation. The column used is an HP-1 quartz capillary column (30m × 0.32mm × 0.25μm), which provides excellent resolution for the target compounds.